TMX-4153

• CAT Number: I041180
• CAS Number: 2867519-91-1
• Molecular Formula: C59H67ClN10O6S
• Molecular Weight: 1079.74
• Purity: ≥95%
• Synonyms: (2S,4R)-1-[(2S)-2-[[7-[2-[5-[[5-chloro-4-(3-phenylphenyl)pyrimidin-2-yl]amino]pyridin-3-yl]-1-oxo-2,8-diazaspiro[4.5]decan-8-yl]-7-oxoheptanoyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide
• InChI: InChI=1S/C59H67ClN10O6S/c1-37(39-19-21-41(22-20-39)52-38(2)63-36-77-52)64-54(74)48-31-46(71)35-70(48)55(75)53(58(3,4)5)66-49(72)17-10-7-11-18-50(73)68-26-23-59(24-27-68)25-28-69(56(59)76)45-30-44(32-61-33-45)65-57-62-34-47(60)51(67-57)43-16-12-15-42(29-43)40-13-8-6-9-14-40/h6,8-9,12-16,19-22,29-30,32-34,36-37,46,48,53,71H,7,10-11,17-18,23-28,31,35H2,1-5H3,(H,64,74)(H,66,72)(H,62,65,67)/t37-,46+,48-,53+/m0/s1
• InChIKey: NIQFZCJNEODJTE-CSIWTOAPSA-N
• SMILES: CC1=C(SC=N1)C2=CC=C(C=C2)[C@H](C)NC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)CCCCCC(=O)N4CCC5(CC4)CCN(C5=O)C6=CN=CC(=C6)NC7=NC=C(C(=N7)C8=CC=CC(=C8)C9=CC=CC=C9)Cl)O

TMX-4153（Cat No.:I041180）is a small-molecule inhibitor designed for the treatment of various cancers by targeting specific proteins involved in tumor growth and survival. It demonstrates strong efficacy in preclinical models, particularly in inhibiting pathways critical to cancer cell proliferation. Its potential extends to improving outcomes in resistant cancer types, making it a promising candidate in oncology research. With a favorable pharmacokinetic profile, TMX-4153 could offer a novel therapeutic approach for patients with limited treatment options, enhancing the effectiveness of existing cancer therapies in combination regimens.