TMP778

• CAT Number: I009834
• CAS Number: 1422171-08-1
• Molecular Formula: C31H30N2O4
• Molecular Weight: 494.58
• Purity: ≥95%

TMP778 is a selective inhibitor of RORγt with an IC50 of 5 nM in the Fluorescence Resonance Energy Transfer (FRET) assay and an IC50 of 17 nM in the RORγ assay.

Reference

[1] Cancan Lyu, et al. Eur J Immunol. 2018 Nov;48(11):1810-1816.
[2] Sheng Xiao, et al. Immunity. 2014 Apr 17;40(4):477-89.