TML-6

• CAT Number: I044677
• CAS Number: 1462868-88-7
• Molecular Formula: C30H37NO7
• Molecular Weight: 523.62
• Purity: ≥95%
• Synonyms: (E)-6-(3,4-dimethoxyphenyl)-3-[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]-N,N-diethyl-3-methyl-4-oxohex-5-enamide
• InChI: InChI=1S/C30H37NO7/c1-8-31(9-2)29(34)20-30(3,27(32)16-12-21-10-14-23(35-4)25(18-21)37-6)28(33)17-13-22-11-15-24(36-5)26(19-22)38-7/h10-19H,8-9,20H2,1-7H3/b16-12+,17-13+
• InChIKey: UWVCYNXVZRDWSD-UNZYHPAISA-N
• SMILES: CCN(C(=O)CC(C(=O)/C=C/C1=CC(=C(C=C1)OC)OC)(C(=O)/C=C/C2=CC(=C(C=C2)OC)OC)C)CC

TML-6（Cat No.:I044677）is a synthetic analog of vitamin E (tocotrienol) designed to enhance neuroprotective and antioxidant properties while improving bioavailability. It targets oxidative stress and inflammation pathways implicated in neurodegenerative diseases such as Alzheimer’s and Parkinson’s. TML-6 exhibits strong free radical scavenging activity and modulates cellular signaling involved in neuronal survival, mitochondrial function, and inflammation. Preclinical studies suggest that TML-6 can reduce neuroinflammation, support cognitive function, and protect against neuronal damage. Its optimized pharmacokinetic profile makes it a promising candidate for therapeutic development in aging-related and neurodegenerative conditions.