For research use only. Not for therapeutic Use.
TLR7/8 Agonist 3(CAT: I016941) is a potent small-molecule agonist of Toll-like receptors 7 and 8 (TLR7/8), key pattern recognition receptors involved in innate immune activation. By stimulating TLR7/8 signaling, it induces downstream NF-κB and IRF pathways, leading to cytokine and chemokine production that promote antiviral and antitumor immunity. With its dual TLR7/8 activity, this compound is a valuable tool for immunology, vaccine adjuvant research, and cancer immunotherapy development. It can be used to study innate immune signaling, immune modulation, and therapeutic strategies targeting infectious disease and oncology. TLR7/8 Agonist 3 provides a versatile probe for both in vitro and in vivo applications.
| CAS Number | 642473-95-8 |
| Synonyms | 1-(2-amino-2-methylpropyl)-2-(ethoxymethyl)imidazo[4,5-c]quinolin-4-amine |
| Molecular Formula | C17H23N5O |
| Purity | ≥95% |
| IUPAC Name | 1-(2-amino-2-methylpropyl)-2-(ethoxymethyl)imidazo[4,5-c]quinolin-4-amine |
| InChI | InChI=1S/C17H23N5O/c1-4-23-9-13-21-14-15(22(13)10-17(2,3)19)11-7-5-6-8-12(11)20-16(14)18/h5-8H,4,9-10,19H2,1-3H3,(H2,18,20) |
| InChIKey | SVBZCXQPNPURIX-UHFFFAOYSA-N |
| SMILES | CCOCC1=NC2=C(N1CC(C)(C)N)C3=CC=CC=C3N=C2N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
