TL02-59

  • CAT Number: I018179
  • CAS Number: 1315330-17-6
  • Molecular Formula: C₃₂H₃₄F₃N₅O₄
  • Molecular Weight: 609.64
  • Purity: ≥95%
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TL02-59 (Cat.No:I018179) is an orally active, selective Src-family kinase Fgr inhibitor with an IC50 of 0.03 nM. TL02-59 inhibits Lyn and Hck with IC50s of 0.1 nM and 160 nM, respectively. TL02-59 potently suppresses acute myelogenous leukemia (AML) cell growth.

Catalog Number I018179
CAS Number 1315330-17-6
Molecular Formula

C₃₂H₃₄F₃N₅O₄

Purity 95%
Reference

[1]. Weir MC, et al. Selective Inhibition of the Myeloid Src-Family Kinase Fgr Potently Suppresses AML Cell Growth in Vitro and in Vivo. ACS Chem Biol. 2018 Jun 15;13(6):1551-1559.

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