Tin protoporphyrin IX dichloride

• CAT Number: M066111
• CAS Number: 14325-05-4
• Molecular Formula: C34H32Cl2N4O4Sn
• Molecular Weight: 750.26
• Purity: ≥95%
• IUPAC Name: 3,3'-(14,14-dichloro-2,7,10,21-tetramethyl-11,20-divinyl-14H-5,8-(azeno)-1,12-(metheno[2]epipyrrolometheno)dipyrrolo[1,2-c:2',1'-k][1,3]diaza[2]stannacycloundecine-3,6-diyl)dipropionic acid
• InChI: InChI=1S/C34H34N4O4.2ClH.Sn/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);2*1H;/q;;;+4/p-4/b25-13-,26-
• InChIKey: HDGCWLZQBOZSGG-UHEVNVKKSA-J
• SMILES: [O-]C(CCC1=C(C=C2[N]3=C4C(C)=C2CCC([O-])=O)[N-]([Sn+4]35([Cl-])([Cl-])[N]6=C7C=C(C(C=C)=C8C)[N-]5C8=C4)C(C=C6C(C=C)=C7C)=C1C)=O.[H+].[H+]

Tin protoporphyrin IX dichloride (CAT: M066111) is a potent, competitive heme oxygenase (HO) inhibitor, particularly targeting HO-1 and HO-2 isoforms. By blocking heme degradation, it reduces bilirubin formation and modulates carbon monoxide signaling. SnPP IX has been widely studied for its anti-hyperbilirubinemic properties, showing potential in preventing neonatal jaundice and regulating oxidative stress responses. In experimental models, it influences pathways involved in inflammation, vascular tone, and cellular stress adaptation. With its well-characterized pharmacological profile, Tin protoporphyrin IX dichloride is an important research tool for investigating heme metabolism, redox biology, and therapeutic modulation of HO activity.