For research use only. Not for therapeutic Use.
THP104c（Cat No.:I044022）is a synthetic peptide developed as an inhibitor of the transcriptional coactivator TAZ (WWTR1), which plays a critical role in the Hippo signaling pathway. TAZ is associated with cancer stem cell maintenance, tumor growth, and metastasis. By disrupting TAZ activity, THP104c helps reduce oncogenic transcription and may suppress tumor progression, particularly in aggressive cancers such as breast or lung carcinoma. Its targeted mechanism makes it a valuable tool in cancer biology research, offering insights into Hippo pathway modulation and therapeutic intervention strategies in TAZ-driven malignancies. For research use only.
| CAS Number | 877792-12-6 |
| Synonyms | 2-methoxy-6-[(E)-[(5-phenylthieno[2,3-d]pyrimidin-4-yl)hydrazinylidene]methyl]phenol |
| Molecular Formula | C20H16N4O2S |
| Purity | ≥95% |
| IUPAC Name | 2-methoxy-6-[(E)-[(5-phenylthieno[2,3-d]pyrimidin-4-yl)hydrazinylidene]methyl]phenol |
| InChI | InChI=1S/C20H16N4O2S/c1-26-16-9-5-8-14(18(16)25)10-23-24-19-17-15(13-6-3-2-4-7-13)11-27-20(17)22-12-21-19/h2-12,25H,1H3,(H,21,22,24)/b23-10+ |
| InChIKey | SHKPGEAUAUBOMX-AUEPDCJTSA-N |
| SMILES | COC1=CC=CC(=C1O)/C=N/NC2=C3C(=CSC3=NC=N2)C4=CC=CC=C4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
