Thiol-PEG4-alcohol

• CAT Number: I016288
• CAS Number: 90952-27-5
• Molecular Formula: C8H18O4S
• Molecular Weight: 210.29
• Purity: ≥95%
• Synonyms: 2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethanol
• InChI: InChI=1S/C8H18O4S/c9-1-2-10-3-4-11-5-6-12-7-8-13/h9,13H,1-8H2
• InChIKey: GKKYNULPAQDGHI-UHFFFAOYSA-N
• SMILES: C(COCCOCCOCCS)O

Thiol-PEG4-alcohol(CAT: I016288) is a heterobifunctional polyethylene glycol (PEG) linker composed of a thiol group on one terminus and a hydroxyl group on the other, separated by a four-unit PEG spacer. The thiol moiety enables selective conjugation to maleimide-, haloacetyl-, or gold-surface groups, forming stable thioether or thiolate linkages. Meanwhile, the hydroxyl group serves as a versatile site for further chemical modification or activation. The PEG4 chain provides moderate flexibility, hydrophilicity, and solubility, helping to reduce steric hindrance in conjugation processes. This reagent is useful in bioconjugation, surface engineering, nanomaterial functionalization, and drug delivery research where short PEG spacers are preferred.