Thiochrome

• CAT Number: I017515
• CAS Number: 92-35-3
• Molecular Formula: C12H14N4OS
• Molecular Weight: 262.33
• Purity: ≥95%
• Synonyms: 2-(6,12-dimethyl-4-thia-2,7,11,13-tetrazatricyclo[7.4.0.03,7]trideca-1(13),2,5,9,11-pentaen-5-yl)ethanol
• InChI: InChI=1S/C12H14N4OS/c1-7-10(3-4-17)18-12-15-11-9(6-16(7)12)5-13-8(2)14-11/h5,17H,3-4,6H2,1-2H3
• InChIKey: GTQXMAIXVFLYKF-UHFFFAOYSA-N
• SMILES: CC1=C(SC2=NC3=NC(=NC=C3CN12)C)CCO

Thiochrome(CAT: I017515) is a tricyclic heteroaromatic compound formed by the oxidation of thiamine (vitamin B₁). It is widely used as a fluorescent derivative in analytical chemistry for the sensitive detection and quantification of thiamine in biological samples, food, and pharmaceuticals. Upon oxidation, thiamine converts to thiochrome, which exhibits strong blue fluorescence under UV light, making it suitable for fluorometric assays and HPLC-based analysis. Beyond its analytical role, thiochrome is also used in biochemical studies of thiamine metabolism and enzyme cofactors. As a reliable marker of vitamin B₁ content, thiochrome is an essential reference compound in nutritional, clinical, and biochemical research.