For research use only. Not for therapeutic Use.
Tetrahydropapaverine hydrochloride(CAT: R055031) is a hydrogenated derivative of the isoquinoline alkaloid papaverine, belonging to the benzylisoquinoline family. This compound is primarily used as a pharmacological tool in studies of smooth muscle physiology and vascular regulation. Compared with papaverine, tetrahydropapaverine shows altered pharmacokinetic and pharmacodynamic properties, making it useful for investigating vasodilation, calcium channel modulation, and cyclic nucleotide metabolism. It has been applied in cardiovascular and neuropharmacological research to explore smooth muscle relaxation mechanisms and cerebrovascular function. As a hydrochloride salt, it offers enhanced solubility and stability, supporting its use in biochemical assays, receptor binding studies, and drug discovery.
| CAS Number | 6429-04-5 |
| Synonyms | 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline;hydrochloride |
| Molecular Formula | C20H26ClNO4 |
| Purity | ≥95% |
| IUPAC Name | 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline;hydrochloride |
| InChI | InChI=1S/C20H25NO4.ClH/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16;/h5-6,10-12,16,21H,7-9H2,1-4H3;1H |
| InChIKey | VMPLLPIDRGXFTQ-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C(C=C1)CC2C3=CC(=C(C=C3CCN2)OC)OC)OC.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
