Tetrahydrodeoxycorticosterone-d3

• CAT Number: I043939
• CAS Number: 72205-58-4
• Molecular Formula: C21H31D3O3
• Molecular Weight: 337.51
• Purity: ≥95%
• Synonyms: 2,2-dideuterio-1-[(3R,5R,8R,9S,10S,13S,14S,17S)-17-deuterio-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-hydroxyethanone
• IUPAC Name: 2,2-dideuterio-1-[(3R,5R,17S)-17-deuterio-3-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-hydroxyethanone
• InChI: InChI=1S/C21H34O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h13-18,22-23H,3-12H2,1-2H3/t13-,14-,15?,16?,17?,18-,20?,21?/m1/s1/i12D2,18D 18D
• InChIKey: CYKYBWRSLLXBOW-SWAHQGBNSA-N
• SMILES: [2H][C@@]1(CCC2C1(CCC3C2CC[C@H]4C3(CC[C@H](C4)O)C)C)C(=O)C([2H])([2H])O

Tetrahydrodeoxycorticosterone-d3 (Cat No.:I043939) is a deuterium-labeled analog of tetrahydrodeoxycorticosterone, a neuroactive steroid involved in modulating GABA_A receptor activity. The incorporation of three deuterium atoms enables its precise quantification via mass spectrometry, making it a valuable internal standard in neurosteroid and endocrine research. THDOC-d3 plays a key role in studying the biosynthesis, metabolism, and physiological effects of neurosteroids, particularly in stress response, mood regulation, and seizure susceptibility. It is widely used in pharmacokinetic studies and to explore neurosteroid function in neurological disorders such as epilepsy, anxiety, and depression.