For research use only. Not for therapeutic Use.
Tetrahydrocortisone(CAT: R047817) is an endogenous steroid metabolite formed during the hepatic reduction of cortisone and cortisol. As a major urinary metabolite of glucocorticoids, it is often measured in clinical and biochemical research to evaluate adrenal function, corticosteroid metabolism, and stress-related hormone regulation. Tetrahydrocortisone serves as an important biomarker in endocrine studies, particularly in disorders involving altered cortisol metabolism such as Cushing’s syndrome, Addison’s disease, and congenital adrenal hyperplasia. Its quantification is also used in metabolic profiling and pharmacokinetic studies of corticosteroid drugs. Tetrahydrocortisone is a valuable analytical standard in endocrinology, steroid metabolism research, and clinical diagnostic applications.
| CAS Number | 53-05-4 |
| Synonyms | (3R,5R,8S,9S,10S,13S,14S,17R)-3,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one |
| Molecular Formula | C21H32O5 |
| Purity | ≥95% |
| IUPAC Name | (3R,5R,8S,9S,10S,13S,14S,17R)-3,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one |
| InChI | InChI=1S/C21H32O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12-15,18,22-23,26H,3-11H2,1-2H3/t12-,13-,14+,15+,18-,19+,20+,21+/m1/s1 |
| InChIKey | SYGWGHVTLUBCEM-ZIZPXRJBSA-N |
| SMILES | CC12CCC(CC1CCC3C2C(=O)CC4(C3CCC4(C(=O)CO)O)C)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
