Tetrahydro-4-pyranol

• CAT Number: R017583
• CAS Number: 2081-44-9
• Molecular Formula: C5H10O2
• Molecular Weight: 102.13
• Purity: ≥95%
• Synonyms: Tetrahydropyran-4-ol; 4-Hydroxytetrahydro-2H-pyran; 4-Hydroxytetrahydropyran; Tetrahydro-2H-pyran-4-ol; Tetrahydro-2H-pyranol-4-ol; Tetrahydro-4-pyranol
• Storage: Store at -20 C
• IUPAC Name: oxan-4-ol
• InChI: InChI=1S/C5H10O2/c6-5-1-3-7-4-2-5/h5-6H,1-4H2
• InChIKey: LMYJGUNNJIDROI-UHFFFAOYSA-N
• SMILES: C1COCCC1O

Tetrahydro-4-pyranol（Cat No.:R017583）, also known as 4-hydroxytetrahydropyran, is a six-membered heterocyclic compound featuring both ether and alcohol functionalities. This bifunctional structure makes it a versatile intermediate in organic synthesis, especially in the development of pharmaceuticals, agrochemicals, and specialty chemicals. Its hydroxyl group provides reactivity for esterification and etherification, while the saturated ring system offers stability and solubility in polar and non-polar solvents. Tetrahydro-4-pyranol is also employed as a building block in carbohydrate chemistry and fine chemical manufacturing, where controlled reactivity and functional group compatibility are essential.

Reference

1.Yamaguchi, Aritomo, et al. "Enhancement of cyclic ether formation from polyalcohol compounds in high temperature liquid water by high pressure carbon dioxide." Green Chemistry 11.1 (2009): 48-52.