Tetraethylammonium Chloride - CAS 56-34-8

K+ channels blocker; cholinoreceptors antagonist; ganglioblocker.


8H20ClN–>, synthetic.

The exposure of rat tracheal segments to threshold/subthreshold concentrations of TEA produces remarkable Airway Hyperresponsiveness (AH) to cooling provocation [Chand N.].

K+ channel blockade is involved in the induction of non specific AH in this model [4]. At the concentration of 10 mM: EC50 = 3.4 �M (1.8 – 6.4).

1 mM blocks InsP3-induced Ca2+ release in microsomal fractions isolated from rat brain incubated in media containing 100 mM KCl. Decreases the InsP3-induced Ca2+ release by 80 � 5% [5].


Catalog Number: R064028

CAS Number: 56-34-8

PubChem Substance ID:355429203

Molecular Formula: C8H20ClN

Molecular Weight:165.705

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

SynonymsN,N,N-Triethyl-ethanaminium Chloride; Etamon Chloride; TEA; TEA Chloride; TEAC; TEAC 100

Property

Molecular Formula: C8H20ClN
Molecular Weight165.705
Target:Potassium Channel
SolubilitySoluble to 100 mM in sterile water
Purity≥95%
StorageDesiccate at RT

Computed Descriptor

IUPAC Nametetraethylazanium;chloride
InChIInChI=1S/C8H20N.ClH/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1
InChIKeyYMBCJWGVCUEGHA-UHFFFAOYSA-M
SMILESCC[N+](CC)(CC)CC.[Cl-]