tert-Butylethyne

• CAT Number: R020297
• CAS Number: 917-92-0
• Molecular Formula: C6H10
• Molecular Weight: 82.15
• Purity: ≥95%
• Synonyms: 3,3,3-Trimethylpropyne; 3,3-Dimethyl-1-butyne; 3,3-Dimethylbut-1-yne; 3,3-Dimethylbutyne; Neohexyne; tert-Butylacetylene
• Storage: -20°C
• IUPAC Name: 3,3-dimethylbut-1-yne
• InChI: InChI=1S/C6H10/c1-5-6(2,3)4/h1H,2-4H3
• InChIKey: PPWNCLVNXGCGAF-UHFFFAOYSA-N
• SMILES: CC(C)(C)C#C

tert-Butylethyne（Cat No.:R020297）is a terminal alkyne featuring a bulky tert-butyl group, offering unique steric and electronic properties that make it valuable in organic synthesis. Its structure supports selective reactions in metal-catalyzed couplings such as Sonogashira and cycloaddition reactions, often used in the synthesis of complex molecules, pharmaceuticals, and advanced materials. The steric hindrance provided by the tert-butyl group enhances stability and influences regioselectivity in downstream transformations. tert-Butylethyne is also employed in developing ligands, dendrimers, and protective groups for synthetic applications where spatial control is critical.