tert-Butyl (S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate

• CAT Number: R022726
• CAS Number: 69610-40-8
• Molecular Formula: C10H19NO3
• Molecular Weight: 201.27
• Purity: ≥95%
• Synonyms: (2S)-2-(Hydroxymethyl)-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester; (2S)-1-(tert-Butoxycarbonyl)-2-pyrrolidinemethanol; (2S)-2-Hydroxymethylpyrrolidine-1-carboxylic Acid tert-butyl Ester; (2S)-Hydroxymethylpyrrolidine-1-carboxylic Acid tert-
• Storage: Store at RT
• IUPAC Name: tert-butyl (2S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate
• InChI: InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-5-8(11)7-12/h8,12H,4-7H2,1-3H3/t8-/m0/s1
• InChIKey: BFFLLBPMZCIGRM-QMMMGPOBSA-N
• SMILES: CC(C)(C)OC(=O)N1CCC[C@H]1CO

tert-Butyl (S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate（Cat No.:R022726）is a chiral, N-Boc-protected pyrrolidine derivative featuring a hydroxymethyl group at the 2-position. The (S)-configuration provides defined stereochemistry, making it useful in asymmetric synthesis and chiral auxiliary development. The tert-butoxycarbonyl (Boc) group protects the nitrogen atom, allowing selective functionalization of the hydroxymethyl group without interference. This compound serves as a valuable intermediate in pharmaceutical research, especially in the synthesis of peptidomimetics, enzyme inhibitors, and CNS-active molecules. Its stability and modular functionality support its role in constructing stereochemically complex bioactive compounds.