tert-Butyl Carbazate

• CAT Number: R022026
• CAS Number: 870-46-2
• Molecular Formula: C5H12N2O2
• Molecular Weight: 132.16
• Purity: ≥95%
• Synonyms: tert-Butyl Ester Carbazic Acid; (tert-Butoxycarbonyl)hydrazide; (tert-Butoxycarbonyl)hydrazine; (tert-Butyloxycarbonyl)hydrazide; 1,1-Dimethylethyl Carbazate; 1,1-Dimethylethyl Hydrazinecarboxylate; 1-(tert-Butoxycarbonyl)hydrazine; Boc-hydrazine; Hy
• Storage: Store at -20°C
• IUPAC Name: tert-butyl N-aminocarbamate
• InChI: InChI=1S/C5H12N2O2/c1-5(2,3)9-4(8)7-6/h6H2,1-3H3,(H,7,8)
• InChIKey: DKACXUFSLUYRFU-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NN

tert-Butyl carbazate(CAT: R022026) is a versatile reagent widely used in organic synthesis, particularly for the preparation of hydrazide and hydrazone derivatives. Featuring a tert-butyl-protected hydrazine moiety, it provides a stable intermediate that can be selectively deprotected under acidic conditions to yield free hydrazine. This compound is commonly employed in peptide synthesis, linker chemistry, and the development of bioactive conjugates such as antibody–drug conjugates (ADCs). Its stability and ease of handling make it ideal for constructing urea, semicarbazide, and other nitrogen-rich structures. tert-Butyl carbazate supports controlled functionalization strategies in pharmaceutical, biochemical, and materials science research.