tert-Butyl 2,2,2-trichloroacetimidate

• CAT Number: R061870
• CAS Number: 98946-18-0
• Molecular Formula: C6H10Cl3NO
• Molecular Weight: 218.50
• Purity: ≥95%
• Synonyms: 2,2,2-Trichloroethanimidic acid tert-butyl ester; O-tert-Butyl trichloroacetimidate; tert-Butyl 2,2,2-trichloroacetimidate; tert-Butyl trichloroacetimidate
• Storage: -20°C
• IUPAC Name: tert-butyl 2,2,2-trichloroethanimidate
• InChI: InChI=1S/C6H10Cl3NO/c1-5(2,3)11-4(10)6(7,8)9/h10H,1-3H3
• InChIKey: CQXDYHPBXDZWBA-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=N)C(Cl)(Cl)Cl

tert-Butyl 2,2,2-trichloroacetimidate（Cat No.:R061870）is a reactive organic intermediate featuring a trichloroacetimidate functional group attached to a tert-butyl moiety. This compound is widely used in glycosylation chemistry as a glycosyl donor, enabling the formation of glycosidic bonds under mild, acid-catalyzed conditions. Its high reactivity stems from the electron-withdrawing trichloromethyl group, which facilitates nucleophilic substitution. The tert-butyl group offers steric bulk and influences solubility. This reagent is valuable in the synthesis of oligosaccharides, natural products, and pharmaceuticals, where precise control over stereoselectivity and functional group compatibility is essential for building complex molecular architectures.