tert-Butyl (2-Chloroethyl)carbamate

• CAT Number: R055451
• CAS Number: 71999-74-1
• Molecular Formula: C7H14ClNO2
• Molecular Weight: 179.64
• Purity: ≥95%
• Synonyms: N-(2-Chloroethyl)carbamic Acid 1,1-Dimethylethyl Ester; 2-[(tert-Butoxycarbonyl)amino]-1-chloroethane; N-(tert-Butoxycarbonyl)-2-chloroethylamine; N-t-Butoxycarbonyl-2-chloroethylamine
• Storage: 4°C
• IUPAC Name: tert-butyl N-(2-chloroethyl)carbamate
• InChI: InChI=1S/C7H14ClNO2/c1-7(2,3)11-6(10)9-5-4-8/h4-5H2,1-3H3,(H,9,10)
• InChIKey: VACLTXTYDFLHJW-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NCCCl

tert-Butyl (2-Chloroethyl)carbamate(CAT: R055451) is a versatile organic intermediate featuring a chloroethyl moiety and a tert-butyl-protected carbamate group. This compound is widely used in medicinal and synthetic organic chemistry, particularly as a masked isocyanate or as a precursor to functionalized amines and heterocycles. The tert-butyl group offers acid-labile protection, enabling selective deprotection under mild conditions. The reactive 2-chloroethyl side chain allows for alkylation and nucleophilic substitution reactions, making it useful in drug design, linker chemistry, and prodrug synthesis.