Terbogel - CAS 149979-74-8

Terbogrel, also known as BIBV-308; BIBV-308-SE; BIBV-308SE, is a thromboxane A2 receptor antagonist potentially for the treatment of pulmonary arterial hypertension. Terbogrel concentration-dependently inhibited collagen (0.6 microg/ml)- and U46619 (11alpha,9alpha-epoxymethano-15(S)-hydroxy-prosta-5Z,+ ++13E-dienoic acid) (1 microM)-induced aggregation and thromboxane synthesis of washed human platelets. In this system, terbogrel exhibited an equipotent (IC50 of about 10 nM) activity as thromboxane A2 synthase inhibitor and thromboxane A2 receptor antagonist. Terbogrel appears to be a compound with an equipotent molar potency as thromboxane A2 synthase inhibitor and receptor antagonist.

Catalog Number: M096083

CAS Number: 149979-74-8

PubChem Substance ID:355036429

Molecular Formula: C11H16O

Molecular Weight:0

Purity: ≥95%

* For research use only. Not for human or veterinary use.


Property

Molecular Formula: C11H16O
Molecular Weight0
Target:A2 receptor antagonist
Purity≥95%
StorageStore at -20°C