Terbinafine HCl - CAS 78628-80-5

Terbinafine HCl inhibits ergosterol synthesis by inhibiting squalene epoxidase, used as an antifungal drug.
Terbinafine (50 μM to 100 μM) inhibits only marginally the metabolism of ethoxycoumarin (CYP1A2), tolbutamide (CYP2C9), or ethynylestradiol, CsA, and cortisol. Terbinafine proves to be a potent inhibitor of the CYP2D6-mediated dextromethorphan O-demethylation and bufuralol 1-hydroxylation with IC50values of 0.2 μM and 0.25 μM, respectively.

Catalog Number: A000945

CAS Number: 78628-80-5

PubChem Substance ID:355039771

Molecular Formula: C21H25N • HCl

Molecular Weight:327.9

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

• Synonyms: KWD 2019

Property

• Molecular Formula: C21H25N • HCl
• Molecular Weight: 327.9
• Target: Squalene epoxidase
• Solubility: >16.3mg/mL in DMSO
• Purity: ≥95%
• Storage: 3 years -20C powder

Computed Descriptor

• InChIKey: BWMISRWJRUSYEX-SZKNIZGXSA-N