TEPC466(Cat No.:I043958)is a monoclonal antibody that specifically targets human immunoglobulin E (IgE), playing a crucial role in allergy and immunology research. By binding to the Fc region of IgE, TEPC466 helps inhibit its interaction with FcεRI receptors on mast cells and basophils, thereby reducing allergic responses and histamine release. It is commonly used in diagnostic assays and laboratory studies to detect or quantify IgE levels. TEPC466 is valuable for understanding IgE-mediated hypersensitivity, allergy mechanisms, and for developing therapeutic strategies targeting IgE in conditions like asthma, eczema, and other allergic diseases.