Tenuifoliside C

• CAT Number: R072732
• CAS Number: 139726-37-7
• Molecular Formula: C35H44O19
• Molecular Weight: 768.71
• Purity: ≥95%
• Synonyms: [(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[(2S,3S,4R,5R)-4-hydroxy-2,5-bis(hydroxymethyl)-3-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxyoxolan-2-yl]oxyoxan-2-yl]methyl (E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate
• InChI: InChI=1S/C35H44O19/c1-45-19-10-17(11-20(46-2)27(19)40)6-8-25(38)50-15-24-28(41)30(43)31(44)34(51-24)54-35(16-37)33(29(42)23(14-36)53-35)52-26(39)9-7-18-12-21(47-3)32(49-5)22(13-18)48-4/h6-13,23-24,28-31,33-34,36-37,40-44H,14-16H2,1-5H3/b8-6+,9-7+/t23-,24-,28-,29-,30+,31-,33+,34-,35+/m1/s1
• InChIKey: PMGMZCFZCYRJAG-KQTMLTHJSA-N
• SMILES: COC1=CC(=CC(=C1O)OC)/C=C/C(=O)OC[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)O[C@]3([C@H]([C@@H]([C@H](O3)CO)O)OC(=O)/C=C/C4=CC(=C(C(=C4)OC)OC)OC)CO)O)O)O

Tenuifoliside C（Cat No.:R072732）is a phenylpropanoid glycoside isolated from Polygala tenuifolia, a traditional medicinal herb used in East Asia for cognitive and mood-related disorders. This compound exhibits diverse pharmacological effects, including neuroprotective, antidepressant, antioxidant, and anti-inflammatory activities. Studies suggest that tenuifoliside C can modulate neurotransmitter systems, reduce oxidative stress, and protect neurons from apoptosis, thereby supporting memory and learning functions. It has also shown potential in alleviating stress-induced behavioral changes. With these bioactivities, tenuifoliside C is considered a promising natural candidate for therapeutic development in neurodegenerative and psychiatric diseases.