Tentoxin-d3

• CAT Number: R019082
• Molecular Formula: C22H27D3N4O4
• Molecular Weight: 417.52
• Purity: ≥95%
• Synonyms: (3S,6S,12Z)-12-benzylidene-6,7-dimethyl-3-(2-methylpropyl)-1-(trideuteriomethyl)-1,4,7,10-tetrazacyclododecane-2,5,8,11-tetrone
• InChI: InChI=1S/C22H30N4O4/c1-14(2)11-17-22(30)26(5)18(12-16-9-7-6-8-10-16)21(29)23-13-19(27)25(4)15(3)20(28)24-17/h6-10,12,14-15,17H,11,13H2,1-5H3,(H,23,29)(H,24,28)/b18-12-/t15-,17-/m0/s1/i5D3
• InChIKey: SIIRBDOFKDACOK-UBACXKFCSA-N
• SMILES: CC1C(=O)NC(C(=O)N(C(=CC2=CC=CC=C2)C(=O)NCC(=O)N1C)C)CC(C)C

Tentoxin-d₃(CAT: R019082) is a deuterium-labeled analog of Tentoxin (HY-N6717), a naturally occurring cyclic tetrapeptide derived from Alternaria tenuis. Known for its herbicidal activity, Tentoxin induces seedling chlorosis by disrupting chloroplast development and inhibiting cyclic photophosphorylation in plant cells. It acts as an energy transfer inhibitor within the photosynthetic apparatus. Incorporation of deuterium enhances its utility in analytical and pharmacokinetic studies, serving as a stable isotope-labeled standard for mass spectrometry and tracer-based research. Tentoxin-d₃ is a valuable tool for studying plant biochemistry, herbicide mode-of-action, and the metabolic fate of cyclic peptides in both agricultural and biochemical applications.