Tempone-15N,d16

• CAT Number: I045492
• CAS Number: 80404-14-4
• Molecular Formula: 15NC9D16O2
• Molecular Weight: 187.32
• Purity: ≥95%
• InChI: InChI=1S/C9H16NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h5-6H2,1-4H3/i1D3,2D3,3D3,4D3,5D2,6D2,10+1
• InChIKey: WSGDRFHJFJRSFY-ZDYDSYIGSA-N
• SMILES: CC1(CC(=O)CC(N1[O])(C)C)C

Tempone-¹⁵N,d₁₆ (Cat No.: I045492) is a stable isotope–labeled nitroxide spin probe used in electron paramagnetic resonance (EPR) spectroscopy and imaging. It contains a ¹⁵N isotope for enhanced spectral resolution and sixteen deuterium atoms (d₁₆) to reduce hyperfine broadening, improving sensitivity and signal clarity. Tempone-¹⁵N,d₁₆ is applied in studies of molecular dynamics, membrane fluidity, oxygen concentration, and redox status in biological and chemical systems. Its isotopic labeling makes it a valuable tool for advanced biophysical research, enabling precise and high-resolution EPR measurements in complex environments.

Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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