Tegaserod

For research use only. Not for therapeutic Use.

  • CAT Number: M104362
  • CAS Number: 145158-71-0
  • Molecular Formula: C16H23N5O
  • Molecular Weight: 301.39
  • Purity: ≥95%
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Tegaserod(Cat No.:M104362)is a selective serotonin 5-HT₄ receptor partial agonist that enhances gastrointestinal motility by stimulating peristalsis and accelerating intestinal transit. It also modulates visceral sensitivity, reducing abdominal discomfort. Clinically, tegaserod has been used for the short-term treatment of irritable bowel syndrome with constipation (IBS-C) in women and for chronic idiopathic constipation. By activating 5-HT₄ receptors in the enteric nervous system, it increases acetylcholine release, promoting coordinated bowel movements. With a well-characterized safety and efficacy profile, tegaserod remains a valuable agent for studying serotonergic regulation of gut function and motility disorders.


CAS Number 145158-71-0
Synonyms

1-[(E)-(5-methoxy-1H-indol-3-yl)methylideneamino]-2-pentylguanidine

Molecular Formula C16H23N5O
Purity ≥95%
IUPAC Name 1-[(E)-(5-methoxy-1H-indol-3-yl)methylideneamino]-2-pentylguanidine
InChI InChI=1S/C16H23N5O/c1-3-4-5-8-18-16(17)21-20-11-12-10-19-15-7-6-13(22-2)9-14(12)15/h6-7,9-11,19H,3-5,8H2,1-2H3,(H3,17,18,21)/b20-11+
InChIKey IKBKZGMPCYNSLU-RGVLZGJSSA-N
SMILES CCCCCN=C(N)N/N=C/C1=CNC2=C1C=C(C=C2)OC
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