For research use only. Not for therapeutic Use.
TCO-PNB ester(CAT:I016615) is a photocleavable trans-cyclooctene (TCO) derivative bearing a para-nitrobenzyl (PNB) ester functionality. The TCO group participates in rapid, bioorthogonal inverse electron-demand Diels–Alder (IEDDA) reactions with tetrazines, enabling precise labeling and conjugation in biological systems. The PNB ester serves as a light-sensitive protecting group, allowing controlled release or activation of linked molecules upon UV irradiation. This dual functionality makes TCO-PNB ester a versatile reagent in chemical biology, drug delivery, and imaging applications, where spatiotemporal control of molecular interactions is critical. It is particularly useful for designing photo-responsive probes, targeted therapeutics, and advanced biomedical research tools.
| CAS Number | 1438415-89-4 |
| Synonyms | [(1R,4E)-cyclooct-4-en-1-yl] (4-nitrophenyl) carbonate |
| Molecular Formula | C15H17NO5 |
| Purity | ≥95% |
| IUPAC Name | [(1R,4E)-cyclooct-4-en-1-yl] (4-nitrophenyl) carbonate |
| InChI | InChI=1S/C15H17NO5/c17-15(20-13-6-4-2-1-3-5-7-13)21-14-10-8-12(9-11-14)16(18)19/h1-2,8-11,13H,3-7H2/b2-1+/t13-/m0/s1 |
| InChIKey | FJMMADPCDJNXAH-AORQRIRUSA-N |
| SMILES | C1CC=CCCC(C1)OC(=O)OC2=CC=C(C=C2)[N+](=O)[O-] |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
