For research use only. Not for therapeutic Use.
TCN 201（Cat No.:R057578）is a selective, negative allosteric modulator of NMDA receptors containing the GluN2A subunit. By binding at an allosteric site, it reduces receptor activity without competing with glutamate or glycine, enabling precise modulation of excitatory neurotransmission. This pharmacological profile makes TCN 201 a valuable tool in neuroscience research, particularly for studying synaptic plasticity, learning, and memory. Its selectivity helps differentiate GluN2A-mediated signaling from other NMDA receptor subtypes. Researchers employ TCN 201 to investigate mechanisms underlying neurological disorders and potential therapeutic strategies.
| CAS Number | 852918-02-6 |
| Synonyms | N-[[4-(benzamidocarbamoyl)phenyl]methyl]-3-chloro-4-fluorobenzenesulfonamide |
| Molecular Formula | C21H17ClFN3O4S |
| Purity | ≥95% |
| IUPAC Name | N-[[4-(benzamidocarbamoyl)phenyl]methyl]-3-chloro-4-fluorobenzenesulfonamide |
| InChI | InChI=1S/C21H17ClFN3O4S/c22-18-12-17(10-11-19(18)23)31(29,30)24-13-14-6-8-16(9-7-14)21(28)26-25-20(27)15-4-2-1-3-5-15/h1-12,24H,13H2,(H,25,27)(H,26,28) |
| InChIKey | FYIBXBFDXNPBSF-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)C(=O)NNC(=O)C2=CC=C(C=C2)CNS(=O)(=O)C3=CC(=C(C=C3)F)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
