TC-I 15

• CAT Number: R062069
• CAS Number: 916734-43-5
• Molecular Formula: C23H28N4O6S2
• Molecular Weight: 520.62
• Purity: ≥95%
• Synonyms: (2S)-2-[[(4R)-3-(benzenesulfonyl)-5,5-dimethyl-1,3-thiazolidine-4-carbonyl]amino]-3-(benzylcarbamoylamino)propanoic acid
• InChI: InChI=1S/C23H28N4O6S2/c1-23(2)19(27(15-34-23)35(32,33)17-11-7-4-8-12-17)20(28)26-18(21(29)30)14-25-22(31)24-13-16-9-5-3-6-10-16/h3-12,18-19H,13-15H2,1-2H3,(H,26,28)(H,29,30)(H2,24,25,31)/t18-,19+/m0/s1
• InChIKey: XKLHCUGVLCGKKX-RBUKOAKNSA-N
• SMILES: CC1([C@H](N(CS1)S(=O)(=O)C2=CC=CC=C2)C(=O)N[C@@H](CNC(=O)NCC3=CC=CC=C3)C(=O)O)C

TC-I 15（Cat No.:R062069）is a selective small molecule inhibitor targeting the enzyme CDK9 (Cyclin-Dependent Kinase 9), which is involved in regulating transcription elongation and cell cycle progression. By inhibiting CDK9, TC-I 15 disrupts the transcriptional machinery and reduces the expression of key survival genes in cancer cells. This compound shows promise in treating cancers by impairing the ability of tumor cells to proliferate and survive. TC-I 15 is being explored for its potential in oncology, particularly for cancers where CDK9 plays a crucial role in disease progression and resistance to treatment.