TAMRA-PEG3-Azide

• CAT Number: I016417
• CAS Number: 1228100-59-1
• Molecular Formula: C33H38N6O7
• Molecular Weight: 630.69
• Purity: ≥95%
• Synonyms: 5-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethylcarbamoyl]-2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]benzoate
• InChI: InChI=1S/C33H38N6O7/c1-38(2)23-6-9-26-29(20-23)46-30-21-24(39(3)4)7-10-27(30)31(26)25-8-5-22(19-28(25)33(41)42)32(40)35-11-13-43-15-17-45-18-16-44-14-12-36-37-34/h5-10,19-21H,11-18H2,1-4H3,(H-,35,40,41,42)
• InChIKey: YREJCORUQQJQHB-UHFFFAOYSA-N
• SMILES: CN(C)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](C)C)C=C3O2)C4=C(C=C(C=C4)C(=O)NCCOCCOCCOCCN=[N+]=[N-])C(=O)[O-]

TAMRA-PEG3-Azide(CAT: I016417) is a fluorescent probe featuring a TAMRA (tetramethylrhodamine) dye, a short PEG3 spacer, and a reactive azide group. The TAMRA moiety provides bright, photostable fluorescence with excitation/emission maxima around 555/580 nm, making it ideal for imaging and detection applications. The PEG3 spacer enhances solubility, reduces steric hindrance, and improves biomolecule accessibility. The azide group enables bioorthogonal labeling via copper-catalyzed or strain-promoted click chemistry with alkynes, allowing highly selective conjugation under mild conditions. TAMRA-PEG3-Azide is widely used in chemical biology, fluorescence imaging, proteomics, and drug delivery research for precise biomolecule labeling and tracking.