Taltobulin intermediate-3

• CAT Number: I040499
• CAS Number: 610786-69-1
• Molecular Formula: C11H22ClNO2
• Molecular Weight: 235.75
• Purity: ≥95%
• Synonyms: ethyl (E,4S)-2,5-dimethyl-4-(methylamino)hex-2-enoate;hydrochloride
• InChI: InChI=1S/C11H21NO2.ClH/c1-6-14-11(13)9(4)7-10(12-5)8(2)3;/h7-8,10,12H,6H2,1-5H3;1H/b9-7+;/t10-;/m1./s1
• InChIKey: DOGUQADNNOKYBX-NZPHSXCUSA-N
• SMILES: CCOC(=O)C(=CC(C(C)C)NC)C.Cl

Taltobulin Intermediate-3(CAT: I040499) is a crucial building block in the synthetic route of Taltobulin (HY-15584), a highly potent tubulin inhibitor frequently used as a cytotoxic payload in antibody-drug conjugate (ADC) development. As part of the Taltobulin assembly, this intermediate contributes to the final compound’s ability to disrupt microtubule dynamics, induce mitotic arrest, and trigger apoptosis in cancer cells. Taltobulin Intermediate-3 is essential for medicinal chemistry workflows focused on synthesizing targeted chemotherapeutics. Supplied in high purity, it is ideally suited for use in the preparation of Taltobulin derivatives and ADC payload-linker systems for preclinical oncology and drug development research.