Taltobulin intermediate-2

• CAT Number: I040503
• CAS Number: 91133-59-4
• Molecular Formula: C11H12O3
• Molecular Weight: 192.21
• Purity: ≥95%
• Synonyms: 3-methyl-2-oxo-3-phenylbutanoic acid
• InChI: InChI=1S/C11H12O3/c1-11(2,9(12)10(13)14)8-6-4-3-5-7-8/h3-7H,1-2H3,(H,13,14)
• InChIKey: ULDLCYGZHGFPIM-UHFFFAOYSA-N
• SMILES: CC(C)(C1=CC=CC=C1)C(=O)C(=O)O

Taltobulin Intermediate-2(CAT: I040503) is a key building block in the synthetic pathway of Taltobulin (HY-15584), a potent microtubule/tubulin inhibitor widely used as a cytotoxic payload in antibody-drug conjugate (ADC) development. This intermediate contributes to the structural formation of Taltobulin, which disrupts tubulin polymerization, leading to mitotic arrest and apoptosis in rapidly dividing cancer cells. Taltobulin Intermediate-2 is essential for researchers focused on the efficient and scalable synthesis of Taltobulin-based therapeutics. Supplied in high purity, it is ideal for use in oncology drug development, ADC payload-linker strategies, and medicinal chemistry applications targeting microtubule dynamics in cancer treatment.