Taltobulin intermediate-1

• CAT Number: I040501
• CAS Number: 228266-38-4
• Molecular Formula: C17H25NO4
• Molecular Weight: 307.38
• Purity: ≥95%
• Synonyms: (2S)-3-methyl-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-3-phenylbutanoic acid
• InChI: InChI=1S/C17H25NO4/c1-16(2,3)22-15(21)18(6)13(14(19)20)17(4,5)12-10-8-7-9-11-12/h7-11,13H,1-6H3,(H,19,20)/t13-/m1/s1
• InChIKey: ZWQAFCGLXUTMKH-CYBMUJFWSA-N
• SMILES: CC(C)(C)OC(=O)N(C)C(C(=O)O)C(C)(C)C1=CC=CC=C1

Taltobulin Intermediate-1(CAT: I040501) is a key synthetic precursor in the production of Taltobulin (HY-15584), a highly potent tubulin inhibitor frequently employed as a cytotoxic payload in antibody-drug conjugates (ADCs). As an essential component in the multi-step synthesis of Taltobulin, this intermediate enables precise structural assembly for maintaining microtubule-targeting activity. The final drug disrupts tubulin polymerization, triggers mitotic arrest, and promotes apoptosis in proliferating tumor cells. Taltobulin Intermediate-1 is ideal for researchers involved in ADC design, medicinal chemistry, and oncology-focused drug development. Supplied in high purity, it supports scalable and efficient synthesis of next-generation targeted cancer therapeutics.