For research use only. Not for therapeutic Use.
Talatisamine(CAT: R035323) is a C19-diterpenoid alkaloid isolated from Aconitum species, plants traditionally used in East Asian medicine. It is structurally related to other aconitine-type alkaloids and has attracted attention for both its pharmacological potential and toxicological significance. Studies indicate that Talatisamine exhibits notable neuroactive properties, including modulation of ion channels, which may underlie its analgesic and anti-inflammatory effects. At the same time, it displays cardiotoxic and neurotoxic activities characteristic of Aconitum alkaloids, making careful study essential. With its complex diterpenoid skeleton, Talatisamine is a valuable subject for natural product chemistry, pharmacology, and investigations into therapeutic applications balanced against safety considerations.
| CAS Number | 20501-56-8 |
| Synonyms | (2R,3R,4S,5S,6S,8S,13S,16S,17R)-11-ethyl-6,16-dimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecane-4,8-diol |
| Molecular Formula | C24H39NO5 |
| Purity | ≥95% |
| IUPAC Name | (2R,3R,4S,5S,6S,8S,13S,16S,17R)-11-ethyl-6,16-dimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecane-4,8-diol |
| InChI | InChI=1S/C24H39NO5/c1-5-25-11-22(12-28-2)7-6-18(30-4)24-14-8-13-16(29-3)10-23(27,19(14)20(13)26)15(21(24)25)9-17(22)24/h13-21,26-27H,5-12H2,1-4H3/t13-,14-,15?,16+,17-,18+,19-,20+,21?,22+,23+,24?/m1/s1 |
| InChIKey | BDCURAWBZJMFIK-FIIQKEKKSA-N |
| SMILES | CCN1CC2(CCC(C34C2CC(C31)C5(CC(C6CC4C5C6O)OC)O)OC)COC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
