For research use only. Not for therapeutic Use.
Tafluprost acid（Cat No.:R031916）is the active metabolite of tafluprost, a prostaglandin F2α analog used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It binds to the prostanoid FP receptor, enhancing uveoscleral outflow of aqueous humor. Tafluprost acid is often studied in its free acid form for pharmacodynamic, pharmacokinetic, and receptor-binding research. Unlike the prodrug, it does not require hydrolysis for activity. This compound plays a vital role in ophthalmic drug development and mechanistic studies related to intraocular pressure regulation and glaucoma therapy.
| CAS Number | 209860-88-8 |
| Synonyms | (Z)-7-[(1R,2R,3R,5S)-2-[(E)-3,3-difluoro-4-phenoxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoic acid |
| Molecular Formula | C22H28F2O5 |
| Purity | ≥95% |
| IUPAC Name | (Z)-7-[(1R,2R,3R,5S)-2-[(E)-3,3-difluoro-4-phenoxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoic acid |
| InChI | InChI=1S/C22H28F2O5/c23-22(24,15-29-16-8-4-3-5-9-16)13-12-18-17(19(25)14-20(18)26)10-6-1-2-7-11-21(27)28/h1,3-6,8-9,12-13,17-20,25-26H,2,7,10-11,14-15H2,(H,27,28)/b6-1-,13-12+/t17-,18-,19+,20-/m1/s1 |
| InChIKey | KIQXRQVVYTYYAZ-VKVYFNERSA-N |
| SMILES | C1[C@@H]([C@@H]([C@H]([C@@H]1O)/C=C/C(COC2=CC=CC=C2)(F)F)C/C=C\CCCC(=O)O)O |
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| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
