Tabersonine hydrochloride

• CAT Number: I017095
• CAS Number: 29479-00-3
• Molecular Formula: C₂₁H₂₅ClN₂O₂
• Molecular Weight: 372.89
• Purity: ≥95%
• Target: Amyloid-β
• IUPAC Name: methyl (1R,12R,19S)-12-ethyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,9,13-pentaene-10-carboxylate;hydrochloride
• InChI: InChI=1S/C21H24N2O2.ClH/c1-3-20-9-6-11-23-12-10-21(19(20)23)15-7-4-5-8-16(15)22-17(21)14(13-20)18(24)25-2;/h4-9,19,22H,3,10-13H2,1-2H3;1H/t19-,20-,21-;/m0./s1
• InChIKey: BBASQSWPQOKOQI-OCIDDWSYSA-N
• SMILES: CC[C@]12CC(=C3[C@@]4([C@H]1N(CC4)CC=C2)C5=CC=CC=C5N3)C(=O)OC.Cl

Tabersonine hydrochloride（Cat No.:I017095）is a chemical compound derived from Tabernaemontana divaricata, a plant known for its medicinal properties. It is a naturally occurring alkaloid with potential pharmacological effects, including anti-inflammatory, analgesic, and antitumor activities. Tabersonine has shown promise in inhibiting the growth of certain cancer cells and may have neuroprotective properties. The hydrochloride salt form, tabersonine hydrochloride, is typically used in scientific research to study these potential benefits more effectively. However, further studies are necessary to determine its clinical applications, safety, and therapeutic potential in humans.

Reference

[1]. Zhang D, et al. Tabersonine attenuates lipopolysaccharide-induced acute lung injury via suppressing TRAF6 ubiquitination. Biochem Pharmacol. 2018 Aug;154:183-192.