T-2 Toxin

• CAT Number: R058391
• CAS Number: 21259-20-1
• Molecular Formula: C24H34O9
• Molecular Weight: 466.527
• Purity: 99%
• Synonyms: (3α,4β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 4,15-Diacetate 8-(3-Methylbutanoate); 12,13-Epoxytrichothec-9-ene-3α,4β,8α,15-tetrol 4,15-Diacetate 8-Isovalerate; 4β,15-Diacetoxy-8α-(3-methylbutyryloxy)-?12,13-epoxytrichothec-9-en-3α-ol; 8α-(3
• Storage: -20°C
• InChI: InChI=1S/C24H34O9/c1-12(2)7-18(27)32-16-9-23(10-29-14(4)25)17(8-13(16)3)33-21-19(28)20(31-15(5)26)22(23,6)24(21)11-30-24/h8,12,16-17,19-21,28H,7,9-11H2,1-6H3/t16-,17+,19+,20+,21+,22+,23+,24-/m0/s1
• InChIKey: BXFOFFBJRFZBQZ-QYWOHJEZSA-N
• SMILES: CC1=CC2C(CC1OC(=O)CC(C)C)(C3(C(C(C(C34CO4)O2)O)OC(=O)C)C)COC(=O)C

T2 Toxin(cas 21259-20-1) is a trichothecene group mycotoxin, of the most important Fusarium toxins.

Reference

1: Li D, Han J, Guo X, Qu C, Yu F, Wu X. The effects of T-2 toxin on the
prevalence and development of Kashin-Beck disease in China: a meta-analysis and
systematic review. Toxicol Res (Camb). 2016 Feb 18;5(3):731-751. doi:
10.1039/c5tx00377f. eCollection 2016 May 1. Review. PubMed PMID: 30090385; PubMed
Central PMCID: PMC6062151.

2: Wu QH, Wang X, Yang W, Nüssler AK, Xiong LY, Kuča K, Dohnal V, Zhang XJ, Yuan
ZH. Oxidative stress-mediated cytotoxicity and metabolism of T-2 toxin and
deoxynivalenol in animals and humans: an update. Arch Toxicol. 2014
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PubMed PMID: 24894432.

3: Yang L, Zhao Z, Wu A, Deng Y, Zhou Z, Zhang J, Hou J. Determination of
trichothecenes A (T-2 toxin, HT-2 toxin, and diacetoxyscirpenol) in the tissues
of broilers using liquid chromatography coupled to tandem mass spectrometry. J
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10.1016/j.jchromb.2013.10.034. Epub 2013 Oct 25. Review. PubMed PMID: 24231141.

4: Li Y, Wang Z, Beier RC, Shen J, De Smet D, De Saeger S, Zhang S. T-2 toxin, a
trichothecene mycotoxin: review of toxicity, metabolism, and analytical methods.
J Agric Food Chem. 2011 Apr 27;59(8):3441-53. doi: 10.1021/jf200767q. Epub 2011
Mar 25. Review. PubMed PMID: 21417259.

5: Sokolović M, Garaj-Vrhovac V, Simpraga B. T-2 toxin: incidence and toxicity in
poultry. Arh Hig Rada Toksikol. 2008 Mar;59(1):43-52. doi:
10.2478/10004-1254-59-2008-1843. Review. PubMed PMID: 18407870.