SynuClean-D

• CAT Number: I017870
• CAS Number: 685121-45-3
• Molecular Formula: C13H5F3N4O5
• Molecular Weight: 354.20
• Purity: ≥95%
• Synonyms: 5-nitro-6-(3-nitrophenyl)-2-oxo-4-(trifluoromethyl)-1H-pyridine-3-carbonitrile
• InChI: InChI=1S/C13H5F3N4O5/c14-13(15,16)9-8(5-17)12(21)18-10(11(9)20(24)25)6-2-1-3-7(4-6)19(22)23/h1-4H,(H,18,21)
• InChIKey: OJRLTEJFYMZKQB-UHFFFAOYSA-N
• SMILES: C1=CC(=CC(=C1)[N+](=O)[O-])C2=C(C(=C(C(=O)N2)C#N)C(F)(F)F)[N+](=O)[O-]

SynuClean-D（Cat No.:I017870）is a small-molecule modulator designed to inhibit the aggregation of α-synuclein, a protein implicated in the pathogenesis of Parkinson’s disease and other synucleinopathies. By binding to α-synuclein, SynuClean-D prevents misfolding and fibril formation, thereby reducing cytotoxic aggregates that disrupt neuronal function. This compound is a valuable research tool for studying protein aggregation, neurodegeneration, and mechanisms underlying Parkinson’s disease progression. SynuClean-D highlights the therapeutic potential of targeting α-synuclein aggregation, offering insights into disease-modifying strategies for neurodegenerative disorders linked to protein misfolding.