Syk-IN-1（Cat No.:I036889）is a potent and selective inhibitor of spleen tyrosine kinase (Syk), a key signaling molecule involved in immune cell activation, particularly in B-cell receptor (BCR) and Fc receptor pathways. By blocking Syk activity, Syk-IN-1 suppresses downstream signaling cascades, including MAPK and NF-κB, thereby reducing inflammation, cell proliferation, and survival. It has demonstrated efficacy in preclinical models of autoimmune diseases, allergic responses, and hematologic malignancies. Syk-IN-1 is a valuable research tool for dissecting Syk-dependent signaling mechanisms and exploring therapeutic strategies targeting immune-mediated and oncogenic disorders.