For research use only. Not for therapeutic Use.
SW157765（Cat No.:I044454）is a synthetic small-molecule activator of the nuclear receptor Nurr1 (NR4A2), a transcription factor essential for the development and maintenance of dopaminergic neurons. By enhancing Nurr1 activity, SW157765 promotes the expression of neuroprotective and anti-inflammatory genes, making it a promising compound for neurodegenerative disease research, particularly in Parkinson’s disease. It has demonstrated the ability to reduce neuroinflammation and support neuronal survival in preclinical models. SW157765 is a valuable pharmacological tool for studying Nurr1-regulated pathways and exploring therapeutic strategies aimed at neuroprotection and inflammatory modulation in central nervous system disorders.
| CAS Number | 332063-87-3 |
| Synonyms | (E)-3-(furan-2-yl)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)prop-2-enamide |
| Molecular Formula | C19H13N3O3 |
| Purity | ≥95% |
| IUPAC Name | (E)-3-(furan-2-yl)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)prop-2-enamide |
| InChI | InChI=1S/C19H13N3O3/c23-18(6-4-15-2-1-11-24-15)21-14-3-5-17-16(12-14)22-19(25-17)13-7-9-20-10-8-13/h1-12H,(H,21,23)/b6-4+ |
| InChIKey | QSSYRORXXFTVFI-GQCTYLIASA-N |
| SMILES | C1=COC(=C1)/C=C/C(=O)NC2=CC3=C(C=C2)OC(=N3)C4=CC=NC=C4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
