For research use only. Not for therapeutic Use.
SulfoxFluor (Cat No.: I045324) is a highly efficient, shelf-stable fluorinating reagent used for the direct conversion of alcohols into alkyl fluorides under mild conditions. It operates via a nucleophilic substitution mechanism, enabling fluorination without the need for preactivation or harsh reagents. SulfoxFluor demonstrates broad substrate compatibility, functional group tolerance, and excellent regioselectivity, making it valuable in medicinal and synthetic chemistry. Its ease of use and stability make it a practical alternative for incorporating fluorine into complex molecules, especially in drug discovery and development.
| CAS Number | 2143892-50-4 |
| Synonyms | N-[(4-chlorophenyl)-fluoro-oxo-λ6-sulfanylidene]-4-methylbenzenesulfonamide |
| Molecular Formula | C13H11ClFNO3S2 |
| Purity | ≥95% |
| InChI | InChI=1S/C13H11ClFNO3S2/c1-10-2-6-13(7-3-10)21(18,19)16-20(15,17)12-8-4-11(14)5-9-12/h2-9H,1H3 |
| InChIKey | ZKSTYVIGFNZFRW-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)N=S(=O)(C2=CC=C(C=C2)Cl)F |
| Reference | [1]. Guo J, et al. Rapid Deoxyfluorination of Alcohols with N-Tosyl-4-chlorobenzenesulfonimidoyl Fluoride (SulfoxFluor) at Room Temperature. Chemistry. 2019;25(30):7259-7264. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
