Sulfopin（Cat No.:I036826）is a selective, covalent inhibitor of Pin1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1), an enzyme involved in regulating protein function through isomerization of phosphorylated serine/threonine-proline motifs. By irreversibly binding to Pin1’s active site, Sulfopin disrupts pathways related to cell cycle progression, apoptosis, and oncogenic signaling. It has demonstrated anticancer activity in preclinical models, particularly in MYC-driven tumors, by impairing tumor cell proliferation and survival. Sulfopin is a valuable tool for studying Pin1 biology and exploring therapeutic strategies targeting proline isomerase activity in cancer and other proliferative disorders.