Sulfo-SPP

• CAT Number: I017799
• CAS Number: 452072-27-4
• Molecular Formula: C14H16N2O7S3
• Molecular Weight: 420.48
• Purity: ≥95%
• Synonyms: 2,5-dioxo-1-[4-(pyridin-2-yldisulfanyl)pentanoyloxy]pyrrolidine-3-sulfonic acid
• InChI: InChI=1S/C14H16N2O7S3/c1-9(24-25-11-4-2-3-7-15-11)5-6-13(18)23-16-12(17)8-10(14(16)19)26(20,21)22/h2-4,7,9-10H,5-6,8H2,1H3,(H,20,21,22)
• InChIKey: ORKSBKSSOSUJOY-UHFFFAOYSA-N
• SMILES: CC(CCC(=O)ON1C(=O)CC(C1=O)S(=O)(=O)O)SSC2=CC=CC=N2

Sulfo-SPP（Cat No.:I017799）is a water-soluble, sulfonated photoaffinity probe widely used in chemical biology and proteomics. It contains a photoreactive group that covalently binds nearby biomolecules upon light activation, enabling the capture of transient or weak protein–ligand interactions. The sulfonate moiety enhances solubility and reduces nonspecific binding, improving labeling efficiency in complex biological systems. Sulfo-SPP is particularly valuable for mapping binding sites, identifying protein partners, and studying dynamic signaling networks. Its versatile design supports advanced applications in target identification, drug discovery, and functional proteomic research.