Sulfo DBCO-PEG4-amine

• CAT Number: I016057
• CAS Number: 2055198-05-3
• Molecular Formula: C32H42N4O10S
• Molecular Weight: 674.76
• Purity: ≥95%
• Synonyms: 3-[3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]propanoylamino]-1-[[3-(11,12-dihydro-6H-benzo[c][1]benzazocin-5-yl)-3-oxopropyl]amino]-1-oxopropane-2-sulfonic acid

Sulfo DBCO-PEG4-amine（Cat No.:I016057）is a water-soluble heterobifunctional linker bearing a sulfonated dibenzocyclooctyne (DBCO) group and a primary amine, separated by a PEG4 spacer. The sulfo-DBCO moiety enables efficient, copper-free strain-promoted azide–alkyne cycloaddition (SPAAC) with azides under physiological conditions, ensuring fast and bioorthogonal conjugation. The terminal amine offers a versatile handle for coupling with activated esters, carboxylic acids, or other electrophiles, expanding functionalization options. The PEG4 chain enhances solubility, flexibility, and minimizes steric hindrance. This reagent is highly useful in bioconjugation, drug delivery, surface modification, and chemical biology applications.