Sulfachloropyridazine-d4

• CAT Number: R057888
• CAS Number: 1795037-54-5
• Molecular Formula: C10H5D4ClN4O2S
• Molecular Weight: 288.75
• Purity: ≥95%
• Synonyms: 4-amino-N-(6-chloropyridazin-3-yl)-2,3,5,6-tetradeuteriobenzenesulfonamide
• InChI: InChI=1S/C10H9ClN4O2S/c11-9-5-6-10(14-13-9)15-18(16,17)8-3-1-7(12)2-4-8/h1-6H,12H2,(H,14,15)/i1D,2D,3D,4D
• InChIKey: XOXHILFPRYWFOD-RHQRLBAQSA-N
• SMILES: C1=CC(=CC=C1N)S(=O)(=O)NC2=NN=C(C=C2)Cl

Sulfachloropyridazine-d4 (Cat No.: R057888) is a deuterium-labeled isotopologue of sulfachloropyridazine, a sulfonamide antibiotic used in veterinary medicine to treat bacterial infections. The incorporation of four deuterium atoms enhances its utility as an internal standard in mass spectrometry and pharmacokinetic studies, enabling precise quantification and analysis in biological samples. Sulfachloropyridazine-d4 retains the chemical properties of the parent compound, making it ideal for studying drug metabolism, residue analysis in food-producing animals, and environmental monitoring of sulfonamide antibiotic contamination with improved analytical accuracy.

Reference

[1]. Dirany A, et al. Electrochemical treatment of the antibiotic sulfachloropyridazine: kinetics, reaction pathways, and toxicity evolution. Environ Sci Technol. 2012 Apr 3;46(7):4074-82
[Content Brief]

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[Content Brief]