SU5204

For research use only. Not for therapeutic Use.

  • CAT Number: I044345
  • CAS Number: 186611-11-0
  • Molecular Formula: C17H15NO2
  • Molecular Weight: 265.31
  • Purity: ≥95%
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SU5204(Cat No.:I044345)is a synthetic small-molecule inhibitor targeting vascular endothelial growth factor receptor 2 (VEGFR-2), a key mediator in angiogenesis. By blocking VEGFR-2 signaling, SU5204 disrupts blood vessel formation, making it a promising candidate in cancer therapy, especially for tumors reliant on angiogenesis for growth and metastasis. Additionally, SU5204 has shown potential in modulating other tyrosine kinases involved in tumor progression. Preclinical studies suggest it can reduce tumor vascularization and enhance the efficacy of chemotherapeutics. Its anti-angiogenic properties position SU5204 as a valuable compound in oncology research.


CAS Number 186611-11-0
Synonyms

(3Z)-3-[(2-ethoxyphenyl)methylidene]-1H-indol-2-one

Molecular Formula C17H15NO2
Purity ≥95%
IUPAC Name (3Z)-3-[(2-ethoxyphenyl)methylidene]-1H-indol-2-one
InChI InChI=1S/C17H15NO2/c1-2-20-16-10-6-3-7-12(16)11-14-13-8-4-5-9-15(13)18-17(14)19/h3-11H,2H2,1H3,(H,18,19)/b14-11-
InChIKey MEZFKCPUSMBMAY-KAMYIIQDSA-N
SMILES CCOC1=CC=CC=C1/C=C\2/C3=CC=CC=C3NC2=O
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