For research use only. Not for therapeutic Use.
SU16f（Cat No.:I010737）is a potent small-molecule inhibitor that primarily targets vascular endothelial growth factor receptor 2 (VEGFR2/KDR) and platelet-derived growth factor receptor (PDGFR). By disrupting receptor tyrosine kinase activity, it interferes with angiogenesis and tumor vascularization, making it a valuable tool in cancer research. SU16f is widely employed in studies exploring anti-angiogenic mechanisms, tumor progression, and vascular signaling pathways. Its inhibitory profile also provides insights into cardiovascular and inflammatory processes regulated by growth factor signaling.
| CAS Number | 251356-45-3 |
| Synonyms | 3-[2,4-dimethyl-5-[(Z)-(2-oxo-6-phenyl-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid |
| Molecular Formula | C24H22N2O3 |
| Purity | ≥95% |
| IUPAC Name | 3-[2,4-dimethyl-5-[(Z)-(2-oxo-6-phenyl-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid |
| InChI | InChI=1S/C24H22N2O3/c1-14-18(10-11-23(27)28)15(2)25-21(14)13-20-19-9-8-17(12-22(19)26-24(20)29)16-6-4-3-5-7-16/h3-9,12-13,25H,10-11H2,1-2H3,(H,26,29)(H,27,28)/b20-13- |
| InChIKey | APYYTEJNOZQZNA-MOSHPQCFSA-N |
| SMILES | CC1=C(NC(=C1CCC(=O)O)C)/C=C\2/C3=C(C=C(C=C3)C4=CC=CC=C4)NC2=O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
