For research use only. Not for therapeutic Use.
Stressin I (Cyclo(31-34)[DPhe¹²,Nle²¹,³⁸,Glu³¹,Lys³⁴]Ac-hCRF(4-41)) TFA(CAT: I040248) is a highly potent and selective agonist for the corticotropin-releasing factor 1 (CRF₁) receptor, exhibiting a Ki of 1.7 nM. This cyclic peptide analog of human CRF(4-41) is widely used to study hypothalamic-pituitary-adrenal (HPA) axis activation and stress-related signaling. In vivo, Stressin I significantly elevates adrenocorticotropic hormone (ACTH) levels in rats, making it a valuable pharmacological tool in neuroendocrinology, behavioral stress research, and CRF₁-targeted drug development. Its enhanced receptor specificity and efficacy enable precise interrogation of CRF₁-mediated physiological and behavioral responses.
| Molecular Formula | C203H337N57O56.xC2HF3O2 |
| Purity | ≥95% |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
