STING agonist-7

• CAT Number: I044071
• CAS Number: 2767442-46-4
• Molecular Formula: C17H12N4O4
• Molecular Weight: 336.30
• Purity: ≥95%
• Synonyms: 2-[(pyrazolo[1,5-a]pyrimidine-3-carbonylamino)methyl]-1-benzofuran-7-carboxylic acid
• InChI: InChI=1S/C17H12N4O4/c22-16(13-9-20-21-6-2-5-18-15(13)21)19-8-11-7-10-3-1-4-12(17(23)24)14(10)25-11/h1-7,9H,8H2,(H,19,22)(H,23,24)
• InChIKey: BICDHWPHEXMVAT-UHFFFAOYSA-N
• SMILES: C1=CC2=C(C(=C1)C(=O)O)OC(=C2)CNC(=O)C3=C4N=CC=CN4N=C3

STING agonist-7（Cat No.:I044071）is a potent small-molecule activator of the STING (Stimulator of Interferon Genes) pathway, a crucial component of the innate immune response. By binding to the STING protein, it induces type I interferon production and activates downstream signaling involved in anti-viral defense and anti-tumor immunity. STING agonist-7 is widely used in cancer immunotherapy research, particularly for enhancing T cell infiltration and overcoming immune evasion in solid tumors. It also holds promise in vaccine adjuvant development and in studying autoimmune or inflammatory responses driven by cyclic dinucleotide signaling.