(S,S,S)-2-Azabicyclo[3.3.0]octane-3-carboxylic Acid, Benzyl Ester, Hydrochloride

• CAT Number: R005448
• CAS Number: 87269-87-2
• Molecular Formula: C15H20ClNO2
• Molecular Weight: 281.78
• Purity: ≥95%
• Synonyms: (2S,3aS,6aS)-octahydro-Cyclopenta[b]pyrrole-2-carboxylic acid
• Storage: -20°C
• IUPAC Name: benzyl (2S,3aS,6aS)-1,2,3,3a,4,5,6,6a-octahydrocyclopenta[b]pyrrole-2-carboxylate;hydrochloride
• InChI: InChI=1S/C15H19NO2.ClH/c17-15(18-10-11-5-2-1-3-6-11)14-9-12-7-4-8-13(12)16-14;/h1-3,5-6,12-14,16H,4,7-10H2;1H/t12-,13-,14-;/m0./s1
• InChIKey: HLXCXOQXUDRJLF-JKBZPBJLSA-N
• SMILES: C1CC2CC(NC2C1)C(=O)OCC3=CC=CC=C3.Cl

(S,S,S)-2-Azabicyclo[3.3.0]octane-3-carboxylic acid, benzyl ester, hydrochloride (Cat No.: R005448) is a chiral bicyclic amino acid derivative with potential applications in medicinal chemistry and peptide design. Its rigid 2-azabicyclo[3.3.0]octane framework enhances conformational constraint, beneficial for receptor selectivity and stability in bioactive compounds. The benzyl ester aids in solubility and protects the carboxyl group during synthesis, while the hydrochloride form improves stability and handling. This compound is particularly useful in developing CNS-active molecules and structure–activity relationship (SAR) studies involving constrained amino acid analogs.